BTCy

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BTCy

CAS No. :

MCE 国际站：BTCy

产品活性：BTCy 是一种近红外 (NIR) 荧光探针，具有极性响应和细胞质膜靶向特性。BTCy 可用于肿瘤组织的体内成像 (λ_ex = 561 nm, λ_em = 600-700 nm)。

研究领域：Others

作用靶点：Fluorescent Dye

In Vitro: BTCy (0-50 μM; 24 h) has low cytotoxicity and is biocompatible for living cells.BTCy exhibits good fluorescence stability and is able to detect the polarity change selectively.
BTCy (10 μM) stains HeLa and HepG2 cells. The cell plasma membrane is specifically and strongly lit up after being stained for 0.5–5 h. The fluorescence intensity of BTCy on the cell plasma membrane shows slight reduction after 2 h.
BTCy (0.1-10 μM; 30 min) stain shows specific fluorescence on the cell plasma membrane even at a low concentration at 100 nM in HeLa cells.
BTCy (0.1-10 μM; 30 min) can be used for monitoring cell plasma membrane polarity variation during the ferroptosis process.

In Vivo: BTCy (0.5 mg/mL; 25 μL; in situ injection) presents a significantly strong and long-time sustained fluorescence signal in the tumor area compared with the normal tissue in the 4T1-tumor-bearing mice.

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