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Eleven-Nineteen-Leukemia Protein IN-1
CAS No. : 2894121-68-5
MCE 国际站：Eleven-Nineteen-Leukemia Protein IN-1
产品活性：Eleven-Nineteen-Leukemia Protein IN-1 是一种 ENL YEATS 域的抑制剂，IC50 值为 14.5 nM。Eleven-Nineteen-Leukemia Protein IN-1 与 ENL 蛋白相互作用并增强 ENL 蛋白的体外热稳定性。
研究领域：Epigenetics
作用靶点：Epigenetic Reader Domain
In Vitro: Eleven-Nineteen-Leukemia Protein IN-1 (compound 13) has inhibition on MOLM-13 cells and MV4-11 cells with IC50 values of 39.6 µM, 45.1 µM, respectively.
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文献和实验【共享】08新书：Protein Engineering (Nucleic Acids and Molecular Biology).pdf
, has proven to be one of the most important advances in biology. By allowing the site-specific replacement of any amino acid in a protein with one of the other nineteen amino acids, it ushered in the new era of "Protein Engineering". The field of protein
Oligonucleotide Microarray Analysis of Gene Expression in Leukemia
(1 ) and to identify new disease classes (2 -7 ) or drug targets (8 ). Other uses include genotyping (9 ), comparative genomic hybridization (10 ), and analysis of DNA-protein interaction (11 ). The amount of data produced by these experiments is formidable
Quantitative Analysis of PRAME for Detection of Minimal Residual Disease in Leukemia
for a 509-amino-acid protein whose function has not yet been identified. PRAME is expressed in various types of cancer, including melanoma (97%), sarcoma (80%), small-cell lung cancer (70%), renal cell carcinoma (40%), and head and neck cancer (29
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