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- 动物熏烟暴露装置
- 2026年04月24日
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- 保修期：
12个月
- 现货状态：
现货
采用精密的卷烟或者电子烟烟雾发生器和机械控制单元，通过产生烟气，使动物持续吸入，用于卷烟或者电子烟烟气毒理实验，可以建立小鼠、大鼠、豚鼠的COPD等相关疾病模型。
性能特点：
采用可调式滑轨注射模块控制卷烟或者电子烟烟雾抽吸量
自动化吸烟，提高实验的一致性和可重复性
抽吸频率和时长可调
烟雾管道易于拆卸，便于清洗或更换
产生的气溶胶粒径为肺部可沉积范围
暴露腔采用透明材质，方便观察
精密流量计可以便于调节烟气浓度
配有烟气滤膜采样模块，全面监测烟气暴露
具有废气处理模块，达到实验室安全排放要求
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文献和实验effect
and
acute
toxicity
test
of
D-borneol
refreshing
atomization
solution
on
mice
Tian
Xinhui1,
Chen
Hongbo2,
Cheng
Fang2,
Han
Yuhang2,
Yang
Xinrui2,
Su
Dandan2,
Li
Siqi1,
Huang
Xiaoling1,
Liu
Chunyan4,
Pang
Yuxin1,3∗
(1.
School
of
Traditional
Medicine
Materials
Resource,
Guangdong
Pharmaceutical
University,
Yunfu
527322,
Guangdong
Province,
China;
2.
School
of
Pharmaceutical
Sciences,
Shenzhen
Campus
of
Sun
Yat-sen
University,
Shenzhen
518107,
Guangdong
Province,
China;
3.
School
of
Pharmacy,
Guizhou
University
of
Traditional
Chinese
Medicine,
Guiyang
550025,
China;
4.
School
of
Agronomy,
Henan
Agricultural
University,
Zhengzhou,
China
450046,
China)
【Abstract】 Objective
To
investigate
the
anti-fatigue
effects
and
acute
toxicity
of
different
doses
of
D-borneol
refreshing
atomization
solution
on
mice,
and
to
provide
reference
for
the
further
development
and
application
of
D-borneol
refreshing
atomization
solution
in
clinic.
Methods Sixty
specifc
pathogen
free
(SPF)
male
KM
mice
were
divided
into
one
blank
group
and
four
dose
groups,
with
12
mice
in
each
group,
for
acute
toxicity
experiments
and
weight-bearing
swimming
experiments.
In
the
acute
toxicity
test,
the
toxic
reaction
of
mice
was
observed.
After
dissection,
histopathological
examination
was
performed.
For
weight-bearing
swimming
experiment,
serum,
liver
and
hind
leg
muscle
tissues
of
mice
were
collected.
Blood
glucose
(Glu),
lactic
acid
(LA),
blood
urea
nitrogen
(BUN),
and
lactate
dehydrogenase
(LDH)
activity
levels
were
measured
in
serum.
Liver
glycogen
(LG)
content
was
assessed
in
liver
tissue;
muscle
glycogen
(MG)
and
other
anti-fatigue
biochemical
indicators
were
evaluated
in
muscle
tissue.
Malondialdehyde
(MDA)
content
and
the
activities
of
superoxide
dismutase
(SOD)
and
glutathione
peroxidase
(GSH-Px)
were
determined
in
muscle
tissue.
Results During
the
administration
of
D-borneol
refreshing
atomization
solution,
no
abnormalities
were
observed
in
the
mental
state,
fur
color,
or
body
weight
of
mice
across
all
groups
during
the
acute
toxicity
test.
Pathological
examinations
did
not
reveal
any
abnormalities
either.
The
weight-
bearing
swimming
test
results
demonstrated
that
medium
and
high
doses
of
D-borneol
refreshing
atomization
solution
could
effectively
prolong
the
time
of
weight-bearing
exhaustive
swimming
in
mice
(P<0. 001),
significantly
increase
the
content
of
MG
(P<0. 01),
and
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小鼠长期暴露于高温环境，即将两种动物长期处在热中性区上临界温度（upper critical temperatures, UCT）的环境中，当小型哺乳类动物处于该环境中时，热传导率的降低会使它们的体温趋于升高，但代谢率持续维持在较低水平以减少产热，又可以避免体温过高。 研究结果发现，两种动物的代谢率降低，而体温升高，寿命均显著缩短，低代谢率并没有延长它们的寿命，但高体温使它们的寿命变短。这表明，对寿命来说，在一定温度范围内体温似乎是比代谢更重要的影响因素。 活得「凉爽」，寿命变长
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