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- 库存：
大量
- 英文名：
SenTraGor™ reagent – 20mg
- 保质期：
5年
- 供应商：
汉诺生物
- 保存条件：
室温
- 规格：
20mg
抗体增强试剂（SenTraGor reagent) 染色可以检测任何生物材料的衰老。可以在所有存档组织标本（福尔马林固定石蜡包埋）和活检或细胞培养物中直接观察衰老细胞。senTraGor染色后，再用荧光抗体进行免疫组化，然后将图像进行合并，可以得到非常清晰的衰老细胞检测图。
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文献和实验In situ evidence of cellular senescence in Thymic Epithelial Cells (TECs) during human thymic involution,
Mechanisms of Ageing and Development,Volume 177,2019,Pages 88-90,ISSN 0047-6374,https://doi.org/10.1016/j.mad.2018.02.005.
(https://www.sciencedirect.com/science/article/pii/S0047637417303007)
Abstract: Cellular senescence, an age-related process in response to damage and stress, also occurs during normal development and adult life. The thymus is a central lymphoepithelial organ of the immune system that exhibits age-related changes termed thymic involution. Since the mechanisms regulating thymic involution are still not well elucidated, we questioned whether cellular senescence is implicated in this process. We demonstrate, for the first time in situ, that cellular senescence occurs during human thymic involution using SenTraGor™, a novel chemical compound that is applicable in archival tissue material, providing thus further insights in thymus histophysiology.
Keywords: Thymic involution; Cellular senescence; SenTraGorTM; Lipofuscin
: 55° C for 30 s c. Extend: 72° C for 1 min 30 s 5) Incubate for an additional 10 min at 72° C and maintain the reaction at 4° C. The samples can be stored at –20° C until use. 6) Analyze the amplification products by agarose gel
Cationic Liposome-Mediated Transfection with Lipofectin Reagent
(2 ,3 ). Some encouraging DNA-delivery results have been obtained; however, the methodology has had some fundamental diffkulties (4 –8 ). Chief among these is that liposomes do not generally fuse with the target cell surface, but are taken up phagocytically
Combinatorial Library Design from Reagent Pharmacophore Fingerprints
starting point for deriving a structure–activity relationship (SAR).
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