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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
2-8℃
- 保质期:
三年
- 英文名:
Verapamil
- 库存:
99
- 供应商:
上海源叶生物科技有限公司
- CAS号:
52-53-9
- 规格:
100mg
分子式:C27H38N2O4
分子量:454.6
外观:\N
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文献和实验陆佳璐, 邓丽娜. 姜黄素-色氨酸共无定型的制备及其在大鼠体内的药动学研究[J]. 中国药房, 2019(17):2348-2354.
Wang, Jinli, et al. "In vitro synergistic effect of baicalin with azithromycin against Staphylococcus saprophyticus isolated from francolins with ophthalmia." Poultry science 98.1 (2019): 373-380.https://doi.org/10.3382/ps/pey356
Wang, Xin, et al. "Differences of first-pass effect in the liver and intestine contribute to the stereoselective pharmacokinetics of rhynchophylline and isorhynchophylline epimers in rats." Journal of ethnopharmacology 209 (2017): 175-183.https://doi.org/1
Rong Huang et al."Surfactant-free solid dispersion of BCS class IV drug in an amorphous chitosan oligosaccharide matrix for concomitant dissolution in vitro - permeability increase."Eur J Pharm Sci. 2019 Mar;130:147
Xin Wang et al."Differences of first-pass effect in the liver and intestine contribute to the stereoselective pharmacokinetics of rhynchophylline and isorhynchophylline epimers in rats."J Ethnopharmacol. 2017 Sep;209:175
Huang Yuanjia et al."Molecular cloning and characterization of calmodulin-like protein CaLP from the Scleractinian coral Galaxea astreata."Cell Stress Chaperon. 2018 Nov;23(6):1329-1335
Yanming Xia et al."Transport mechanism of ursodeoxycholic acid in human placental BeWo cells."Biopharm Drug Dispos. 2018 Jul;39(7):335-343
Juanhong Zhang et al."Enhanced P-glycoprotein expression under high-altitude hypoxia contributes to increased phenytoin levels and reduced clearance in rats."Eur J Pharm Sci. 2020 Oct;153:105490
Jinli Wang et al."In vitro synergistic effect of baicalin with azithromycin against Staphylococcus saprophyticus isolated from francolins with ophthalmia."Poultry Sci. 2019 Jan;98:373
Xiao-Hang Liu et al."Comparison of the permeability between conjugated estrogens and atenolol in rat in situ single-pass intestinal perfusions model and in Caco-2 cell monolayers."J Drug Deliv Sci Tec. 2022 Feb;68:102786
网络 第三节 常用钙拮抗药 维拉帕米 维拉帕米(verapamil)又名异搏定(isoptin)。 【药理作用】维拉帕米在离体实验能降低窦房结起搏细胞自律性,减慢窦性频率,但在整体实验中,此作用被反射性的交感神经兴奋所部分抵消,人体用药后窦性频率减慢约10%,对房室
,需要时选用β受体阻断药,也可选用维拉帕米。 2.心房纤颤或扑动转律用奎尼丁(宜先给强心甙),或与普萘洛尔合用,预防复发可加用或单用胺碘酮,控制心室频率用强心甙或加用维拉帕米或普萘洛尔。 3.房性早搏必要时选用普萘洛尔,维拉帕米,胺碘酮,次选奎尼丁,普鲁卡因胺,丙吡胺。 4.阵发性室上性心动过速除先用兴奋迷走神经的方法外,可选用维拉帕米、普萘洛尔、胺碘酮、奎尼丁、普罗帕酮。 5.室性早搏必要时首选普鲁卡因胺、丙吡胺、美西律、妥卡尼、胺碘酮,急性心肌梗塞时宜用利多
PriCells: 利用Hoechst 33342外流性质分选原代角膜间质干细胞
利用Hoechst 33342外流性质分选原代角膜间质干细胞 试剂和材料: 1. 2—4代的间质细胞; 2. HBSS/2FB; 3. Hoechst 33342染料,1mg/ml水溶; 4. 碘化丙啶(PI),2mg/ml水溶; 5. 维拉帕米,500μg/ml水溶; 6. DEME/2FB; 7. 胰蛋白酶/TrypLE:TrypLE Express或0.25%胰蛋白酶,溶于CMF-Saline G; 8. MoFlo(或与其类似的)高速细胞分选仪,具备350nm激发能力
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