Anti-LRP5 Polyclonal Antibody

产品简介

英文名称	Anti-LRP5 Polyclonal Antibody
中文名称	低密度脂蛋白受体相关蛋白5抗体
别名	BMND1;EVR1;EVR4;HBM;LR3;LRP-5;LRP7;OPPG;OPS;OPTA1;VBCH2;LDL receptor related protein 5
背景资料	This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants.
Swiss Prot	O75197
Gene ID	4041
亚细胞定位	Endoplasmic reticulum Membrane Single-pass type I membrane protein
宿主	Rabbit
克隆类型	Polyclonal Antibody
亚型	IgG
蛋白分子量	179kDa
稀释比例	WB 1:500-2000.
免疫原	A synthetic peptide of human LRP5
Public Immunogen Range	A synthetic peptide of human LRP5
纯化方法	Affinity purification
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
保存	Store at -20°C. Avoid freeze / thaw cycles.
性状	液体
交叉反应	Human
应用	WB
规格	50ul 100ul
单位	支

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
温馨提示：
使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.
实验图

Western blot analysis with LRP5 antibody at dilution at 1:1000