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- 详细信息
- 文献和实验
- 技术资料
- 靶点:
SENP6
- 应用范围:
WB
- 宿主:
Rabbit
- 适应物种:
Human;Mouse
- 保质期:
一年
- 供应商:
北京索莱宝科技有限公司
- 克隆性:
Polyclonal Antibody
- 保存条件:
Store at -20℃. Avoid freeze / thaw cycles.
- 亚型:
IgG
- 免疫原:
A synthetic peptide of human SENP6
- 规格:
50ul
产品简介
| 中文名称 | 泛素样蛋白特异性蛋白酶6抗体 |
| 靶标 | SENP6 |
| 别名 | 2810017C20Rik; FLJ11355; FLJ11887; KIAA0389; KIAA0797; SENP 6; Senp6; SENP6_HUMAN; Sentrin specific protease 6; Sentrin-specific protease 6; Sentrin/SUMO specific protease SENP6; Sentrin/SUMO-specific protease SENP6; SSP 1; SSP1; SUMO 1 specific protease 1; SUMO 1 specific protease; SUMO-1-specific protease 1; SUMO1 specific protease 1; SUMO1 specific protease; SUMO1/sentrin specific peptidase 6; SUSP 1; SUSP1; |
| 背景资料 | Ubiquitin-like molecules (UBLs), such as SUMO1 (UBL1; MIM 601912), are structurally related to ubiquitin (MIM 191339) and can be ligated to target proteins in a similar manner as ubiquitin. However, covalent attachment of UBLs does not result in degradation of the modified proteins. SUMO1 modification is implicated in the targeting of RANGAP1 (MIM 602362) to the nuclear pore complex, as well as in stabilization of I-kappa-B-alpha (NFKBIA; MIM 164008) from degradation by the 26S proteasome. Like ubiquitin, UBLs are synthesized as precursor proteins, with 1 or more amino acids following the C-terminal glycine-glycine residues of the mature UBL protein. Thus, the tail sequences of the UBL precursors need to be removed by UBL-specific proteases, such as SENP6, prior to their conjugation to target proteins (Kim et al., 2000 [PubMed 10799485]). SENPs also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM, Jun 2009] |
| Swiss Prot | Q9GZR1 |
| 亚细胞定位 | Nucleus |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 蛋白分子量 | 125/126KDa |
| 实际分子量 | 102kDa |
| 稀释比例 | WB 1:500-2000. |
| 免疫原 | A synthetic peptide of human SENP6 |
| Public Immunogen Range | 755-805/1112aa |
| 纯化方法 | Affinity purification |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 保存 | Store at -20℃. Avoid freeze / thaw cycles. |
| 交叉反应 | Human;Mouse |
| 应用 | WB |
| 规格 | 50ul 100ul |
| 单位 | 支 |
备注:
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
温馨提示:
使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.
实验图
"Western blot analysis with SENP6 antibody diluted at 1:1000;Lane: K-562
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文献和实验Polyclonal Antibody Production
, if desired this is best accomplished by Protein A Affinity Chromatography. 上一篇:make an Antibody against a Peptides 下一篇:Immunization Protocol for Monoclonal Antibody Production
Polyclonal Antibody Production
Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation. Rabbit Immunization Initial Preparation Your antigen
a simple ELISA method to detect human anti-antibody response.
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