Anti-AIFM1 Polyclonal Antibody

产品简介

单位	支
英文名称	Anti-AIFM1 Polyclonal Antibody
别名	AIF;CMT2D;CMTX4;COWCK;COXPD6;DFNX5;NADMR;NAMSD;PDCD8
宿主	Rabbit
稀释比例	WB 1:500-2000.IHC 1:50-200.IF 1:50-200.IP 1:50-100
Gene ID	9131
保存	Store at -20°C. Avoid freeze / thaw cycles.
Swiss Prot	O95831
蛋白分子量	67kDa
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
亚细胞定位	Cytoplasm Mitochondrion inner membrane Mitochondrion intermembrane space Nucleus perinuclear region
免疫原	Recombinant protein of human AIFM1
亚型	IgG
性状	液体
纯化方法	Affinity purification
背景资料	This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6 (COXPD6), a severe mitochondrial encephalomyopathy, as well as Cowchock syndrome, also known as X-linked recessive Charcot-Marie-Tooth disease-4 (CMTX-4), a disorder resulting in neuropathy, and axonal and motor-sensory defects with deafness and mental retardation. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10.
Public Immunogen Range	Recombinant protein of human AIFM1
克隆类型	Polyclonal Antibody
交叉反应	Human Rat Mouse
应用	WB IP IF IHC
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
温馨提示：
使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.
实验图

Western blot analysis with AIFM1 antibody diluted at 1:1000

Immunohistochemistry of paraffin-embedded Breast cancer(hu) using AIFM1 antibody at dilution of 1:100 (x100 lens��x200 lens).