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- 详细信息
- 技术资料
- 免疫原:
Recombinant protein of human ACVR1
- 亚型:
IgG
- 形态:
液体/冻干粉
- 保存条件:
Store at -20℃. Avoid freeze / thaw cycles.
- 克隆性:
单克隆
- 标记物:
Biotin,Cy3,Cy3.5,Cy5,Cy5.5,Cy7,FITC,HRP,RBITC,SAlexa Fluor 350,SAlexa Fluor 405,SAlexa Fluor 488,SAlexa Fluor 532,SAlexa Fluor 555,SAlexa Fluor 568,SAlexa Fluor 594,SAlexa Fluor 633,SAlexa Fluor 640,SAlexa Fluor 647,SAlexa Fluor 660,SAlexa Fluor 680,SAlexa Fluor 750
- 适应物种:
Human;Mouse;Rat
- 保质期:
一年
- 抗原来源:
Recombinant protein of human ACVR1
- 目录编号:
K112649P
- 级别:
科研级别
- 库存:
999
- 供应商:
北京索莱宝科技有限公司
- 宿主:
Rabbit
- 应用范围:
WB;IHC
- 浓度:
WB 1:2000-5000. IHC 1:25-100.
- 靶点:
ACVR1
- 抗体英文名:
Anti-ACVR1 Polyclonal Antibody
- 抗体名:
激活素 A 受体, I 型抗体
- 规格:
50ul/100ul
| 规格: | 50ul | 产品价格: | ¥960.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1600.0 |
Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive.
实验图
Western blot analysis with ACVR1 antibody diluted at 1:3000;Lane: Rat brain.
Immunohistochemistry of paraffin-embedded human breast cancer with ACVR1 antibody diluted at 1:50.
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