Anti-PLCG1 Polyclonal Antibody

产品简介

单位	支
英文名称	Anti-PLCG1 Polyclonal Antibody
别名	NCKAP3;PLC-II;PLC1;PLC148;PLCgamma1
宿主	Rabbit
稀释比例	WB 1:500-2000
Gene ID	5335
保存	Store at -20°C. Avoid freeze / thaw cycles.
Swiss Prot	P19174
蛋白分子量	149kDa
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
亚细胞定位	Cell projection lamellipodium ruffle
免疫原	A synthetic peptide of human PLCG1
亚型	IgG
性状	液体
纯化方法	Affinity purification
背景资料	The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.
Public Immunogen Range	A synthetic peptide of human PLCG1
克隆类型	Polyclonal Antibody
交叉反应	Human Rat Mouse
应用	WB
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
温馨提示：
使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.
实验图

Western blot analysis with PLCG1 antibody diluted at 1:1000