- ￥960 - 1600
- Solarbio
- 北京
- K111994P
- 2025年07月11日
- IHC
- Rabbit
- Human;Mouse
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- 详细信息
- 技术资料
- 免疫原：
Recombinant protein of human ANKRD27
- 亚型：
IgG
- 形态：
液体/冻干粉
- 保存条件：
Store at -20℃. Avoid freeze / thaw cycles.
- 克隆性：
Polyclonal Antibody
- 标记物：
Biotin，Cy3，Cy3.5，Cy5，Cy5.5，Cy7，FITC，HRP，RBITC，SAlexa Fluor 350，SAlexa Fluor 405，SAlexa Fluor 488，SAlexa Fluor 532，SAlexa Fluor 555，SAlexa Fluor 568，SAlexa Fluor 594，SAlexa Fluor 633，SAlexa Fluor 640，SAlexa Fluor 647，SAlexa Fluor 660，SAlexa Fluor 680，SAlexa Fluor 750
- 适应物种：
Human;Mouse
- 保质期：
一年
- 抗原来源：
Recombinant protein of human ANKRD27
- 目录编号：
84079
- 级别：
科研级别
- 库存：
999
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Rabbit
- 应用范围：
IHC
- 浓度：
IHC 1:100-300.
- 靶点：
ANKRD27
- 抗体英文名：
Anti-ANKRD27 Polyclonal Antibody
- 抗体名：
锚蛋白重复结构域27抗体
- 规格：
50ul/100ul
| 规格： | 50ul | 产品价格： | ￥960.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1600.0 |
May be a guanine exchange factor (GEF) for Rab21, Rab32 and Rab38 and regulate endosome dynamics. May regulate the participation of VAMP7 in membrane fusion events; in vitro inhibits VAMP7-mediated SNARE complex formation by trapping VAMP7 in a closed, fusogenically inactive conformation. Involved in peripheral melanosomal distribution of TYRP1 in melanocytes; the function, which probably is implicating vesicle-trafficking, includes cooperation with Rab32, Rab38 and VAMP7 (By similarity). Involved in the regulation of neurite growth; the function seems to require its GEF activity, probably towards Rab21, and VAMP7 but not Rab32/38 (By similarity). Proposed to be involved in Golgi sorting of VAMP7 and transport of VAMP7 vesicles to the cell surface; the function seems to implicate kinesin heavy chain isoform 5 proteins, GOLGA4, RAB21 and MACF1. Required for the colocalization of VAMP7 and Rab21, probably on TGN sites. Involved in GLUT1 endosome-to-plasma membrane trafficking; the function is dependent of association with VPS29. Regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes (By similarity).
实验图
Immunohistochemistry of paraffin-embedded Human Colorectal cancer with ANKRD27 antibody diluted at 1:200.
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