Anti-STAT6 Polyclonal Antibody

产品简介

单位	支
英文名称	Anti-STAT6 Polyclonal Antibody
别名	STAT6B;STAT6C;D12S1644;IL-4-STAT
宿主	Rabbit
稀释比例	WB 1:500-2000.
Gene ID	6778
保存	Store at -20°C. Avoid freeze / thaw cycles.
Swiss Prot	P42226
蛋白分子量	94kDa
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
亚细胞定位	Cytoplasm Nucleus
免疫原	Recombinant protein of human STAT6
亚型	IgG
性状	液体
纯化方法	Affinity purification
背景资料	The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.
Public Immunogen Range	Recombinant protein of human STAT6
克隆类型	Polyclonal Antibody
交叉反应	Human Mouse
应用	WB
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
温馨提示：
使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.
实验图

Western blot analysis with STAT6 antibody diluted at 1:1000 ;Lane: THP-1