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- 详细信息
- 技术资料
- 免疫原:
A synthetic peptide of human ABL1
- 亚型:
IgG
- 形态:
液体/冻干粉
- 保存条件:
Store at -20°C. Avoid freeze / thaw cycles.
- 克隆性:
单克隆
- 标记物:
Biotin,Cy3,Cy3.5,Cy5,Cy5.5,Cy7,FITC,HRP,RBITC,SAlexa Fluor 350,SAlexa Fluor 405,SAlexa Fluor 488,SAlexa Fluor 532,SAlexa Fluor 555,SAlexa Fluor 568,SAlexa Fluor 594,SAlexa Fluor 633,SAlexa Fluor 640,SAlexa Fluor 647,SAlexa Fluor 660,SAlexa Fluor 680,SAlexa Fluor 750
- 适应物种:
Human ; Mouse ; Rat
- 保质期:
1-3年;详询
- 目录编号:
K001657P
- 级别:
科研级别
- 库存:
999
- 供应商:
北京索莱宝科技有限公司
- 宿主:
Rabbit
- 应用范围:
IF ; IHC ; WB
- 浓度:
WB 1:100-500. IHC 1:50-200. IF 1:50-200.
- 靶点:
ABL1
- 抗体英文名:
Anti-ABL1 Polyclonal Antibody
- 抗体名:
ABL;JTK7;bcr/abl;c-ABL;c-ABL1;p150;v-abl
- 规格:
50ul/100ul
| 规格: | 50ul | 产品价格: | ¥2550.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥4150.0 |
This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t(9;22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene (BCR; MIM:151410). Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons.
实验图
Immunohistochemistry of paraffin-embedded human prostate using ABL1 antibody at dilution of 1:100 (x40 lens).
Western blot analysis with ABL1 antibody diluted at 1:1000;Lane: Rat liver.
Immunohistochemistry of paraffin-embedded human breast cancer with ABL1 antibody diluted at 1:150.
Immunofluorescence analysis of A431 cells using ABL1 antibody diluted at 1:100.
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