Anti-MEOX1 Polyclonal Antibody

产品简介

英文名称	Anti-MEOX1 Polyclonal Antibody
中文名称	间充质同源框1抗体
靶标	MEOX1
别名	Homeobox protein MOX-1, MEOX1, MEOX1_HUMAN, Mesenchyme homeo box 1, Mesenchyme homeobox 1, MOX 1, MOX1
背景资料	Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints (PubMed:23290072, PubMed:24073994). Binds specifically to the promoter of target genes and regulates their expression. Activates expression of NKX3-2 in the sclerotome. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome.
Swiss Prot	P50221
Gene ID	4222
亚细胞定位	Cytoplasm Nucleus
宿主	Rabbit
克隆类型	Polyclonal Antibody
亚型	IgG
预测交叉反应	Zebrafish;Chimpanzee
蛋白分子量	16/20/28kDa
稀释比例	WB 1:1000-3000;IHC 1:100-300.
免疫原	Recombinant protein of human MEOX1
Public Immunogen Range	1-255aa
纯化方法	Affinity purification
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
保存	Store at -20°C. Avoid freeze / thaw cycles.
规格	50ul 100ul
单位	支

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
温馨提示：
使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.
实验图

Western blot analysis with MEOX1 antibody diluted at 1:2000;Lane: Mouse lung.

Immunohistochemistry of paraffin-embedded Human colorectal cancer with MEOX1 antibody diluted at 1:200.