AF 10, AF10, AF10_HUMAN, ALL 1 fused gene from chromosome 10, ALL1 fused gene from chromosome 10, ALL1-fused gene from chromosome 10 protein, MLLT 10, MLLT10, Myeloid/lymphoid or mixed lineage leukemia (trithorax homolog Drosophila) translocated to 10, Myeloid/lymphoid or mixed lineage leukemia translocated to 10, Protein AF 10, Protein AF-10, Protein AF10, Type I AF10 protein
背景资料
Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA. In cells, binding to unmodified histone H3 regulates DOT1L functions including histone H3 'Lys-79' dimethylation (H3K79me2) and gene activation.
Swiss Prot
P55197
Gene ID
8028
亚细胞定位
Nucleus Cytoplasm
宿主
Rabbit
克隆类型
Polyclonal Antibody
亚型
IgG
蛋白分子量
14/20/109/113kDa
稀释比例
WB 1:1000-3000.
免疫原
A synthetic peptide of human MLLT10
Public Immunogen Range
520-570/1068aa
纯化方法
Affinity purification
储存液
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
保存
Store at -20°C. Avoid freeze / thaw cycles.
交叉反应
Human;Mouse
应用
WB
规格
50ul 100ul
单位
支
备注:
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
温馨提示:
使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.
实验图
Western blot analysis with MLLT10 antibody diluted at 1:2000;Lane: Mouse testis.