Anti-LIG4 Polyclonal Antibody

产品简介

英文名称	Anti-LIG4 Polyclonal Antibody
中文名称	DNA连接酶4抗体
靶标	LIG4
别名	LIG4, DNA ligase IV ATP dependent, DNA ligase IV ATP dependent, DNA joinase, DNA joinase, DNA ligase 4, DNA ligase IV, DNA repair enzyme, DNA repair enzyme, DNLI4_HUMAN, LIG 4, LIG4, LIG-4, Ligase IV, Ligase IV, Ligase IV DNA ATP dependent, Polydeoxyribonucleotide synthase [ATP] 4, Polydeoxyribonucleotide synthase 4, Polydeoxyribonucleotide synthase, Polydeoxyribonucleotide synthase, Polynucleotide ligase, Polynucleotide ligase, Sealase
背景资料	Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
Swiss Prot	P49917
Gene ID	3981
亚细胞定位	Nucleus Cytoplasm
宿主	Rabbit
克隆类型	Polyclonal Antibody
亚型	IgG
预测交叉反应	Chimpanzee;Chicken;Hamster
蛋白分子量	104kDa
稀释比例	IHC 1:50-200.
免疫原	A synthetic peptide of human LIG4
Public Immunogen Range	425-475/911aa
纯化方法	Affinity purification
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
保存	Store at -20°C. Avoid freeze / thaw cycles.
交叉反应	Human;Mouse
应用	IHC
规格	50ul 100ul
单位	支

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
温馨提示：
使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.
实验图

Immunohistochemistry of paraffin-embedded Human breast cancer with LIG4 antibody diluted at 1:80.

Immunohistochemistry of paraffin-embedded Human pancreatic cancer with LIG4 antibody diluted at 1:80.