Anti-ZAP70 Polyclonal Antibody

产品简介

英文名称	Anti-ZAP70 Polyclonal Antibody
宿主	Rabbit
别名	ZAP70;ADMIO2;IMD48;SRK;STCD;STD;TZK;ZAP-70;tyrosine-protein kinase ZAP-70
稀释比例	WB 1:2000-5000.
蛋白分子量	36/56/70kDa
Gene ID	7535
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human ZAP70
亚细胞定位	Cytoplasm
Swiss Prot	P43403
背景资料	This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.
Public Immunogen Range	1-350aa
克隆类型	Polyclonal Antibody
交叉反应	Human Rat Mouse
应用	WB
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图