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Anti-CHCHD2 Polyclonal Antibod

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  • ¥960 - 1600
  • Solarbio已认证
  • K108146P
  • 北京
  • 2025年07月15日
  • WB IHC
  • Rabbit
  • Human Mouse Rat
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 抗体名

      含coiled-coil-helix结构域蛋白2抗体

    • 抗体英文名

      Anti-CHCHD2 Polyclonal Antibody

    • 靶点

      CHCHD2

    • 浓度

      WB 1:1000-3000. IHC1:100-300.

    • 应用范围

      WB IHC

    • 宿主

      Rabbit

    • 适应物种

      Human Mouse Rat

    • 保质期

      1-3年

    • 抗原来源

      Recombinant protein of human CHCHD2

    • 目录编号

      51142

    • 级别

      科研级别

    • 库存

      999

    • 供应商

      北京索莱宝科技有限公司

    • 标记物

      Biotin,Cy3,Cy3.5,Cy5,Cy5.5,Cy7,FITC,HRP,RBITC,SAlexa Fluor 350,SAlexa Fluor 405,SAlexa Fluor 488,SAlexa Fluor 532,SAlexa Fluor 555,SAlexa Fluor 568,SAlexa Fluor 594,SAlexa Fluor 633,SAlexa Fluor 640,SAlexa Fluor 647,SAlexa Fluor 660,SAlexa Fluor 680,SAlexa Fluor 750

    • 克隆性

      多克隆

    • 保存条件

      Store at -20℃. Avoid freeze / thaw cycles.

    • 形态

      液体/冻干粉

    • 亚型

      IgG

    • 免疫原

      Recombinant protein of human CHCHD2

    • 规格

      50ul/100ul

    规格:50ul产品价格:¥960.0
    规格:100ul产品价格:¥1600.0

    The protein encoded by this gene belongs to a class of eukaryotic CX(9)C proteins characterized by four cysteine residues spaced ten amino acids apart from one another. These residues form disulfide linkages that define a CHCH fold. In response to stress, the protein translocates from the mitochondrial intermembrane space to the nucleus where it binds to a highly conserved 13 nucleotide oxygen responsive element in the promoter of cytochrome oxidase 4I2, a subunit of the terminal enzyme of the electron transport chain. In concert with recombination signal sequence-binding protein J, binding of this protein activates the oxygen responsive element at four percent oxygen. In addition, it has been shown that this protein is a negative regulator of mitochondria-mediated apoptosis. In response to apoptotic stimuli, mitochondrial levels of this protein decrease, allowing BCL2-associated X protein to oligomerize and activate the caspase cascade. Pseudogenes of this gene are found on multiple chromosomes. Alternative splicing results in multiple transcript variants.

    产品细节图片1
    Immunohistochemistry of paraffin-embedded Human colorectal cancer with CHCHD2 antibody diluted at 1:200.

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    图标文献和实验
    相关实验
    • Polyclonal Antibody Production

      , if desired this is best accomplished by Protein A Affinity Chromatography.   上一篇:make an Antibody against a Peptides   下一篇:Immunization Protocol for Monoclonal Antibody Production

    • Polyclonal Antibody Production

        Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation.     Rabbit Immunization Initial Preparation Your antigen

    • Human Anti-antibody Response

      a simple ELISA method to detect human anti-antibody response.

    图标技术资料

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