Anti-NRAS Polyclonal Antibody

产品简介

英文名称	Anti-NRAS Polyclonal Antibody
宿主	Rabbit
别名	ALPS4;CMNS;N-ras;NCMS;NRAS1;NS6
稀释比例	WB 1:3000-5000.
蛋白分子量	21kDa
Gene ID	4893
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	A synthetic peptide of human NRAS
亚细胞定位	Cell membrane Cytoplasm Golgi apparatus Membrane Nucleus
Swiss Prot	P01111
背景资料	This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.
Public Immunogen Range	139-189/189aa
克隆类型	Polyclonal Antibody
交叉反应	Human Pig Rat Mouse
应用	WB
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图

Western blot analysis with NRAS antibody diluted at 1:4000;Lane: SH-SY5Y,HepG2,A431,Mouse brain