Anti-PDX1 Polyclonal Antibody

产品简介

单位	支
英文名称	Anti-PDX1 Polyclonal Antibody
别名	GSF;IDX-1;IPF1;IUF1;MODY4;PAGEN1;PDX-1;STF-1
中文名称	胰岛素促进因子/胰十二指肠同源异型盒蛋白抗体
宿主	Rabbit
稀释比例	WB 1:2000-5000.IHC 1:50-200.
Gene ID	3651
保存	Store at -20°C. Avoid freeze / thaw cycles.
Swiss Prot	P52945
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
蛋白分子量	31Da
亚细胞定位	Cytoplasm Nucleus cytosol
免疫原	A synthetic peptide of human PDX1
亚型	IgG
性状	液体
纯化方法	Affinity purification
背景资料	Activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. Particularly involved in glucose-dependent regulation of insulin gene transcription. As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Binds preferentially the DNA motif 5'-[CT]TAAT[TG]-3'. During development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. At adult stage, required for maintaining the hormone-producing phenotype of the beta-cell.
Public Immunogen Range	A synthetic peptide of human PDX1
克隆类型	Polyclonal Antibody
交叉反应	Human Rat Mouse
应用	WB IHC
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
温馨提示：
使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.
实验图

Western blot analysis with PDX1 antibody at dilution at 1:1000

Immunohistochemistry of paraffin-embedded Pancreatic cancer(hu) using PDX1 at dilution of 1:100 (x100 lens,x200 lens).