产品名称:NLRP13抗体 产品分类 抗体 / 一抗 英文名称 NLRP13 中文名称 NLRP13蛋白抗体 英文别名 LRR and PYD domains-containing protein 13; NACHT; NACHT, LRR and PYD domains-containing protein 13; NAL13_HUMAN; NLRP13; Nucleotide-binding oligomerization domain protein 14. 交叉反应 Human 标记 Unconjugated 抗体来源 Rabbit 抗体类型 Polyclonal 免疫原 KLH conjugated synthetic peptide derived from human NLRP13 蛋白细胞定位 细胞浆 纯化方法 affinity purified by Protein A 亚型 IgG 性状 Liquid 浓度 1mg/ml 储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. 背景资料 NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP13, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [ 12563287]).[supplied by OMIM, Mar 2008]