产品名称:Goat IgM抗体 产品分类: 抗体 / 同型对照 英文名称: Goat IgM 中文名称: 羊IgM(亲和纯化) 英文别名: Goat Immunoglobulin M, native; Native Goat IgM 中文别名:(亲和纯化) 羊IgM; 正常羊免疫球蛋白M 标记 :Unconjugated 性状 保存条件 :Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. 背景资料 IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antis and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to it's high valency IgM is more efficient than other isotypes is binding antis with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The e for the mu constant region contains four domains separated by short intervening sequences.