产品名称:C6ORF173抗体 产品分类 抗体 / 一抗 英文名称 :C6ORF173 中文名称:6号染色体开放阅读框173抗体 英文别名 :cancer upregulated e 2; Cancer-up-regulated e 2 protein; CENP-W; cenpw; CENPW_HUMAN; Centromere protein W; chromosome 6 open reading frame 173; CUG2; hypothetical protein LOC387103. 交叉反应 :Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep 标记 :Unconjugated 抗体来源:Rabbit 抗体类型:Polyclonal 免疫原:KLH conjugated synthetic peptide derived from human C6ORF173 蛋白细胞定位:细胞核 纯化方法:affinity purified by Protein A 亚型:IgG 性状:Liquid 浓度:1mg/ml 储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件:Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. 背景资料 Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation (By similarity). The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres (By similarity). Part of a nucleosome-associated complex that binds specifically to histone H3-containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA. Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly. CENPW has a fundamental role in kinetochore assembly and function. It is one of the inner kinetochore proteins, with most further proteins binding downstream. Required for normal chromosome organization and normal progress through mitosis.