产品名称:PCDHA3抗体 产品分类 抗体 / 一抗 英文名称 :PCDHA3 中文名称:原钙粘附蛋白α3抗体 英文别名 :KIAA0345 like 11; PCDH alpha 3; Protocadherin alpha 3; PCDA3_HUMAN. 交叉反应 :Human, Mouse, Rat, Dog, Horse 标记 :Unconjugated 抗体来源:Rabbit 抗体类型:Polyclonal 免疫原:KLH conjugated synthetic peptide derived from human PCDHA3 蛋白细胞定位:细胞膜 纯化方法:affinity purified by Protein A 亚型:IgG 性状:Liquid 浓度:1mg/ml 储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件:Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. 背景资料 Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin (PCDH) e clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged es. The protein products of PCDH-alpha es interact with Integrin ∫1 to promote cell adhesion and form oligomers with PCDH-gamma proteins at specific membrane sites. PCDHA3 (Protocadherin alpha-3) is a 950 amino acid single-pass transmembrane protein that contains six cadherin domains. PCDHA3 is a unique cadherin in that it likely functions in spermatoesis and may also have a role in organizing germ cell-specific structures, such as the flagellum, acrosome and intercellular bridge. There are two isoforms of PCDHA13 that are produced as a result of alternative splicing events.