产品名称:RNF16/TRIM17抗体 产品分类 抗体 / 一抗 英文名称 :RNF16/TRIM17 中文名称:环指蛋白16抗体 英文别名 :RBCC; RING finger protein 16; RNF16; TERF; Testis RING finger protein; TRIM 17; Tripartite motif protein 17; TRI17_HUMAN. 交叉反应 :Human 标记 :Unconjugated 抗体来源:Rabbit 抗体类型:Polyclonal 免疫原:KLH conjugated synthetic peptide derived from human TRIM17/RNF16 蛋白细胞定位:细胞核,细胞浆 纯化方法:affinity purified by Protein A 亚型:IgG 性状:Liquid 浓度:1mg/ml 储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件:Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. 背景资料 The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. TRIM17 (tripartite motif-containing 17), also known as RBCC, terf or RNF16, is a 477 amino acid protein that contains one RING-type zinc finger, one SPRY domain and one B box-type zinc finger. Expressed nearly exclusively in testis, TRIM17 belongs to the TRIM family and, based on its functional domains, may play a role in transcriptional regulation events. The e encoding TRIM17 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 es and comprises nearly 8% of the human ome. Chromosome 1 houses a large number of disease-associated es, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.