产品名称:NOC2L抗体 产品分类:抗体 / 一抗 英文名称:NOC2L 中文名称 NOC2家族样蛋白抗体 英文别名 NIR; NOC2 like; Novel INHAT (inhibitor of histone acetyltransferase) repressor; Nucleolar complex associated 2 homolog (S. cerevisiae); Protein NOC2 homolog; NOC2L_HUMAN. 交叉反应:Human, Mouse, Rat, Pig, Cow, Sheep 标记: Unconjugated 抗体来源: Rabbit 抗体类型: Polyclonal 免疫原 KLH conjugated synthetic peptide derived from human NOC2L 蛋白细胞定位: 细胞核,细胞浆 纯化方法: affinity purified by Protein A 亚型 IgG 性状: Liquid 浓度: 1mg/ml 储存液: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件: Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. 研究领域: 细胞生物 信号转导 细胞凋亡 转录调节因子 表观遗传学 背景资料: NOC2L is a transcriptional corepressor with inhibitor of histone acetyltransferase (INHAT) activity. NOC2L or NIR (Novel INHAT Repressor) is ubiquitously expressed throughout embryonic development and adulthood. It is a potent transcriptional corepressor that is not blocked by histone deacetylase inhibitors and is capable of silencing both basal and activator-driven transcription. NOC2L directly binds to nucleosomes and core histones and prevents acetylation by histone acetyltransferases, thus acting as a bona fide INHAT.