Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.PubMedPubMed
浓度:
1mg/ml
规格:
100ul
产品属性:
产品名称
英文名称
型号
MAFK抗体
MAFK
GOY-01K1518
产品名称:MAFK抗体 产品分类:抗体 / 一抗 英文名称:MAFK 中文名称 转录因子MAFK抗体 英文别名 Erythroid transcription factor NF E2 p18 subunit; Erythroid transcription factor NF-E2 p18 subunit; FLJ32205; MAFK; MAFK_HUMAN; MGC71717; Nfe2u; P18; Transcription factor MafK; V maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian). 交叉反应:Human, Mouse, Rat, Cow 标记: Unconjugated 抗体来源: Rabbit 抗体类型: Polyclonal 免疫原 KLH conjugated synthetic peptide derived from human MAFK 蛋白细胞定位: 细胞核 纯化方法: affinity purified by Protein A 亚型 IgG 性状: Liquid 浓度: 1mg/ml 储存液: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件: Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. 研究领域: 细胞生物 发育生物学 神经生物学 转录调节因子 表观遗传学 背景资料: The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2 (nuclear factor erythroid-2). NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, porphobilinogen deaminase (PBGD; MIM 609806) and ferrochelatase (FECH; MIM 612386). NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG (MIM 602020), or MafK) and p45 (MIM 601490). Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160). Maf homodimers suppress transcription at NFE2 sites.[supplied by OMIM, Nov 2008]