产品名称:phospho-MAP4K4 (Ser629)抗体 产品分类:抗体 / 一抗 英文名称:phospho-MAP4K4 (Ser629) 中文名称 磷酸化丝裂原活化蛋白激酶MAP4K4抗体 英文别名 MAP4K4(phospho Ser629); MAP4K4(phospho S629); p-MAP4K4(phospho S629); Hepatocyte progenitor kinase like/germinal center kinase like kinase; HGK; HPK/GCK like kinase; HPK/GCK like kinase HGK; KIAA0687; MAPK/ERK kinase kinase kinase 4; MEK kinase kinase 4; MEKKK 4; MEKKK4; Mitogen activated protein kinase kinase kinase kinase 4; Nck interacting kinase; NIK. 交叉反应:Human, Mouse, Rat, Chicken, Dog, Horse, Rabbit 标记: Unconjugated 抗体来源: Rabbit 抗体类型: Polyclonal 免疫原 KLH conjugated Synthesised phosphopeptide derived from human MAP4K4 around the phosphorylation site of Ser629 蛋白细胞定位: 细胞浆 纯化方法: affinity purified by Protein A 亚型 IgG 性状: Liquid 浓度: 1mg/ml 储存液: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件: Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. 研究领域: 肿瘤 免疫学 信号转导 转录调节因子 激酶和磷酸酶 背景资料: MAP4K4 (Mitogen-activated protein kinase kinase kinase kinase 4) belongs to the serine/threonine protein kinase family and specifically activates MAPK8/JNK. It may play a role in the response to environmental stress and is thought to function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF alpha signaling pathway. It interacts with the SH3 domain of the adapter protein Nck. MAP4K4-dependent signaling inhibits PPARG responsive gene expression, adipogenesis, and insulin stimulated glucose transport.