产品名称:DMRTC1抗体 产品分类:抗体 / 一抗 英文名称:DMRTC1 中文名称 DMRTC1蛋白抗体 英文别名 DMRT like family C1; Dmrtc1; DMRTC_HUMAN; DMRTC1B; Doublesex and mab 3 related transcription factor C1; Doublesex mab 3. 交叉反应:Human 标记: Unconjugated 抗体来源: Rabbit 抗体类型: Polyclonal 免疫原 KLH conjugated synthetic peptide derived from human DMRTC1 蛋白细胞定位: 细胞核 纯化方法: affinity purified by Protein A 亚型 IgG 性状: Liquid 浓度: 1mg/ml 储存液: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件: Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. 研究领域: 细胞生物 转录调节因子 表观遗传学 背景资料: DMRTC1 is a 182 amino acid nuclear protein that exists as three alternatively spliced isoforms and belongs to the DMRT family. Involved in sexual development, DMRTC1 is expressed in Sertoli cells in male testis but, unlike other DMRT family members, it does not contain a DM DNA-binding domain. The gene encoding DMRTC1 maps to the human X chromosome, which consists of about 153 million base pairs and nearly 1,000 genes. The combination of an X and Y chromosome lead to normal male development while two copies of X lead to normal female development. There are a number of conditions related to an unsual number and combination of sex chromosomes being inherited, including Klinefelter's syndrome, Turner's syndrome, and Triple X syndrome.