Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.PubMedPubMed
浓度:
1mg/ml
规格:
100ul
产品名称:UNC5D抗体 产品分类:抗体 / 一抗 英文名称:UNC5D 中文名称 神经突起生长诱导因子受体UNC5D抗体 英文别名 UNC5H4; UNC5D; Netrin receptor UNC5D; Netrin receptor Unc5h4; Protein unc 5 homolog D; Unc 5 homolog 4; Unc 5 homolog D (C. elegans); Unc 5 homolog D; UNC 5D; Unc5h4; FLJ16019; KIAA1777. 交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit 标记: Unconjugated 抗体来源: Rabbit 抗体类型: Polyclonal 免疫原 KLH conjugated synthetic peptide derived from human UNC5H4 蛋白细胞定位: 细胞膜 纯化方法: affinity purified by Protein A 亚型 IgG 性状: Liquid 浓度: 1mg/ml 储存液: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件: Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. 研究领域: 细胞生物 神经生物学 背景资料: The UNC5H family of proteins act as transmembrane receptors for netrin-1 and play a crucial role in axon guidance and migration of neural cells. Additionally, when cleaved by a caspase to produce an intracellular fragment containing a death domain,UNC5H receptors induce apoptosis. This activity is blocked by the binding of netrin-1. In the absence of netrin-1, UNC5H receptors act as tumor suppressors by inhibiting anchorage-independent growth and invasion,