产品名称:GCNF抗体 产品分类:抗体 / 一抗 英文名称:GCNF 中文名称 生殖细胞核因子GCNF/维甲酸受体相关睾丸受体抗体 英文别名 GCNF 1; GCNF; GCNF1; Germ cell nuclear factor; hGCNF; hRTR; NR 61; NR61; NR6A1_HUMAN; Nuclear receptor subfamily 6 group A member 1; Orphan nuclear receptor NR6A1; Retinoic acid receptor related testis associated receptor; Retinoid receptor related testis specific receptor; Retinoid receptor-related testis-specific receptor; RTR. 交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit 标记: Unconjugated 抗体来源: Rabbit 抗体类型: Polyclonal 免疫原 KLH conjugated synthetic peptide derived from human GCNF 蛋白细胞定位: 细胞核 纯化方法: affinity purified by Protein A 亚型 IgG 性状: Liquid 浓度: 1mg/ml 储存液: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件: Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. 研究领域: 细胞生物 发育生物学 神经生物学 信号转导 干细胞 转录调节因子 表观遗传学 背景资料: Germ cell nuclear factor (GCNF) is an orphan member of the nuclear receptor gene superfamily that influences neurogenesis and germ cell development. GCNF can homodimerize and bind DNA. GCNF regulates paracrine interaction between the oocyte and somatic cells by regulating the expression of BMP-15 and GDF-9, to affect female fertility. GCNF is present in spermatocytes and round spermatids of adult male mouse testis; northern blot and ribonuclease protection assays have shown GCNF is predominant in the testis. The gene expresses three alternatively spliced transcript variants.