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说明书
说明书
说明书
多克隆
Rabbit
说明书
HRG beta 1
乳腺癌细胞分化因子P45抗体
Unconjugated
说明书
说明书
KLH conjugated synthetic peptide derived from human Neuregulin 1
LgG
液体
说明书
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
1mg/ml
100ul
产品名称 | 浓度 | 型号 |
乳腺癌细胞分化因子P45抗体 | 1mg/ml | EY-01K2081 |
产品名称:乳腺癌细胞分化因子P45抗体 英文名称:HRG beta 1 英文别名:Neuregulin 1; GGF2; Acetylcholine receptor inducing activity; ARIA; Breast cancer cell differentiation factor p45; GGF; glial growth factor; Heregulin; Heregulin beta1; heregulin, alpha (45kD, ERBB2 p185 activator); HGL; HRG; HRG beta 1A; HRG1; HRGA; NDF; neu differentiation factor; NRG1; sensory and motor neuron derived factor; SMDF; NRG1_HUMAN. 中文别名: Heregulinβ 交叉反应: Human, Mouse, Rat, Rabbit 标记: Unconjugated 抗体来源: Rabbit 抗体类型: Polyclonal 免疫原: KLH conjugated synthetic peptide derived from human Neuregulin 1 蛋白细胞定位: 细胞核,细胞膜,分泌型蛋白 纯化方法: affinity purified by Protein A 亚型: IgG 性状: Liquid 浓度: 1mg/ml 储存液: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件: Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. 背景资料: NRG1 (Neuregulin 1) is a ligand for ERBB3 and ERBB4 tyrosine kinase receptors. NRG1 concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. There are multiple isoforms of NRG1, the type I isoforms (isoforms 1-8) have an Ig domain and a glycosylation domain. There are 10 known isoforms in total which perform distinct tissue-specific functions. Type I isoforms are the predominant forms expressed in the endocardium. Isoform alpha is expressed in breast, ovary, testis, prostate, heart, skeletal muscle, lung, placenta liver, kidney, salivary gland, small intestine and brain, but not in uterus, stomach, pancreas, and spleen. Isoform 3 is the predominant form in mesenchymal cells and in nonneuronal organs, whereas isoform 5 is the major neuronal form. Isoform 8 is expressed in spinal cord and brain. |
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