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说明书
说明书
说明书
多克隆
Rabbit
说明书
ENDOD1
核酸内切酶结构域蛋白1抗体
Unconjugated
说明书
说明书
KLH conjugated synthetic peptide derived from human ENDOD1
LgG
液体
说明书
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
1mg/ml
100ul
产品名称 | 浓度 | 型号 |
核酸内切酶结构域蛋白1抗体 | 1mg/ml | EY-01K1276 |
产品名称:核酸内切酶结构域蛋白1抗体 英文名称:ENDOD1 英文别名:C85344; ENDD1_HUMAN; Endonuclease domain containing 1; Endonuclease domain-containing 1 protein; KIAA0830. 交叉反应: Human, Mouse, Rat, Horse 标记: Unconjugated 抗体来源: Rabbit 抗体类型: Polyclonal 免疫原: KLH conjugated synthetic peptide derived from human ENDOD1 蛋白细胞定位: 分泌型蛋白 纯化方法: affinity purified by Protein A 亚型: IgG 性状: Liquid 浓度: 1mg/ml 储存液: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件: Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. 背景资料: ENDOD1 is a 500 amino acid secreted protein that belongs to the DNA/RNA non-specific endonuclease family. ENDOD1 is thought to act as a DNase and an RNase. The gene that encodes ENDOD1 maps to human chromosome 11, which comprises approximately 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes. |
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