Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
适应物种:
Human, Mouse
保质期:
12个月
库存:
现货
宿主:
Rabbit
应用范围:
WB,IP
靶点:
PDGF Receptor beta
规格:
20μL/50μL/100μL
规格:
20μL
产品价格:
¥850.0
规格:
50μL
产品价格:
¥1400.0
规格:
100μL
产品价格:
¥2400.0
This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. [provided by RefSeq, Jun 2013]