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- 2025年12月05日
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- 文献和实验
- 技术资料
- 保存条件：
4°C, stored under nitrogen
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
487-70-7
- 规格：
5 g/10 g
| 规格： | 5 g | 产品价格： | ￥340.0 |
|---|---|---|---|
| 规格： | 10 g | 产品价格： | ￥510.0 |
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2,4,6-Trihydroxybenzaldehyde
CAS No. : 487-70-7
MCE 国际站：2,4,6-Trihydroxybenzaldehyde
产品活性：2,4,6-Trihydroxybenzaldehyde 是一种具有口服活性的 NF-ĸB 抑制剂。2,4,6-Trihydroxybenzaldehyde 具有抗肿瘤活性、抗癌细胞增殖活性和抗肥胖活性。
研究领域：NF-κB
作用靶点：NF-κB
In Vitro: 2,4,6-Trihydroxybenzaldehyde inhibits adipocyte differentiation and lipid accumulation in 3T3-L1 cells.
2,4,6-Trihydroxybenzaldehyde down-regulates PPARγ, C/EBPα, SREBP-1c, and FAS protein expression levels.
In Vivo: 2,4,6-Trihydroxybenzaldehyde (oral administration; 5 and 25 mg/kg for 13 weeks) reduces the HFD-induced increase in weight gain, reduces serum levels of glucose, triglycerides, and total cholesterol.
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甲厂＜45岁组预期发病数=1‰×400=0.4 乙厂＜45岁组预期发病数=1‰×800=0.8 余类推，并合计得甲厂预期发病人数为0.4+1.2=1.6 乙厂预期发病人数为0.8+0.4=1.2 （二）推算标化发病比（SIR），按公式（20.4a） 甲厂石棉肺标化发病比=22/1.6=13.8 乙厂石棉标化发病比=20/1.2=16.7 （三）推算标化发病率，按公式（20.4b
）：Lysosomal lumen alkalizer（溶酶体腔碱化剂） 除了选用上述工具药外，一般还需结合遗传学技术对自噬相关基因进行干预：包括反义 RNA 干扰技术（Knockdown）、突变株筛选、外源基因导入等。 三、自噬过程进行观察和检测 细胞经诱导或抑制后，需对自噬过程进行观察和检测，常用的策略和技术有： 1、观察自噬体的形成 由于自噬体属于亚细胞结构，普通光镜下看不到，因此，直接观察自噬体需在透射电镜下。phagophore的特征为：新月状或杯状，双层或多层膜，有包绕胞浆
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