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- 2025年12月05日
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Oct4 inducer-1
CAS No. : 182564-41-6
MCE 国际站：Oct4 inducer-1
产品活性：Oct4 inducer-1 (compound OAC-3) 是一种有效的 Oct4 激活剂。Oct4 inducer-1 激活 Oct4 和 Nanog 启动子，促进诱导多能干细胞 (iPSC) 的形成。Oct4 inducer-1 通过提高效率和缩短重编程时间，促进了细胞的重编程。
研究领域：Stem Cell/Wnt
作用靶点：Oct3/4
In Vitro: Oct4 inducer-1 (compound OAC-3; 1 μM) enhances reprogramming efficiency by activating Oct4-luc reporter and Nanog-luc reporter in embryonic stem cells (ESCs). Oct4 inducer-1 increases induced pluripotent stem cells (iPSC) generation and accelerates the appearance of iPSC-like colonies.
Oct4 inducer-1 (1 μM; 4F (OSKM) infected mouse embryonic fibroblast (MEF)) enhances reprogramming efficiency in iSF1 media.
相关产品：Bioactive Compound Library Plus | Stem Cell Signaling Compound Library | Anti-Aging Compound Library | Transcription Factor-Targeted Library | OAC1 | O4I2 | OAC2 | O4I1 | Oct3/4-inducer-1 | Trimebutine maleate | Oct4 inducer-2
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文献和实验Activity of the Germline-Specific Oct4-GFP Transgene in Normal and Clone Mouse Embryos
recombination). Transgenes have been generated using different regions of the Oct4 gene promoter to drive expression of either lacZ or GFP, which allows the activity of the Oct4 promoter to be followed in living cells and tissues. The bacterial LacZ gene encodes
Induced Pluripotent Stem Cells (iPSC) from Cord Blood CD133+ Cells Using Oct4 and Sox2
only two transcription factors OCT4 and SOX2. The methods for establishment and maintenance of CB-derived iPS (CB-iPS) cells are similar, with some modifications, to those for human iPSCs derived from fibroblasts. In particular, this protocol includes a detailed
error estimation and a Fisher test. Using these techniques, we determined a PWM for OCT4 which is similar to canonical OCT4 consensus sequence. In a separate study, we also use de novo motif discovery to suggest that ZNF263 binds to a 24-nt site
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