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- 详细信息
- 技术资料
- 保存条件:
零下80~20°C
- 保质期:
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名:
AU-15330
- 库存:
10
- 供应商:
TargetMol
- CAS号:
2380274-50-8
- 规格:
500 mg/25 mg/100 mg/5 mg/10 mg/50 mg/1 mg
| 规格: | 500 mg | 产品价格: | ¥28200.0 |
|---|---|---|---|
| 规格: | 25 mg | 产品价格: | ¥7750.0 |
| 规格: | 100 mg | 产品价格: | ¥13800.0 |
| 规格: | 5 mg | 产品价格: | ¥3390.0 |
| 规格: | 10 mg | 产品价格: | ¥4930.0 |
| 规格: | 50 mg | 产品价格: | ¥9870.0 |
| 规格: | 1 mg | 产品价格: | ¥1330.0 |
Product Introduction
Bioactivity
英文名:AU-15330
描述:AU-15330 is a protein hydrolysis-targeted chimeric (PROTAC) degrader of the SWI/SNF ATPase subunits SMARCA2 and SMARCA4.AU-15330 potently inhibits tumor growth in a prostate cancer xenograft model and acts synergistically with the AR antagonist enzalutamide.AU-15330 shows partial therapeutic efficacy and non-toxicity with the AR antagonist enzalutamide in a desmoplasia-resistant prostate cancer (CRPC) model. AU-15330 showed partial therapeutic efficacy in a denervation-resistant prostate cancer (CRPC) model and AU-15330 was characterized by non-toxicity.

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