- ￥10600
- TargetMol
- 美国
- T39742
- 2025年07月12日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
CXCR4 antagonist 2
- 库存：
10
- 供应商：
TargetMol
- CAS号：
2243636-57-7
- 规格：
25 mg
Product Introduction
Bioactivity
英文名:CXCR4 antagonist 2
描述:CXCR4 antagonist 2 is a CXCR4 antagonist with an IC 50 value of 47 nM.
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文献和实验Hematopoietic Progenitor Cell Collection
Hematopoietic progenitor cells can be mobilized from the bone marrow microenvironment into the peripheral blood following treatment of patients with myeloid cytokines (GCSF, GMCSF, IL3), a CXCR4 antagonist (Plerixafor) and/or following
Combinatorial Stem Cell Mobilization in Animal Models
to perform a bone marrow transplant. Recent studies have shown synergistic mobilization of HPCs when G-CSF pretreatment is combined with acute administration of a CXCR4 antagonist suggesting that combinatorial therapies may have therapeutic potential
, as illustrated by the homodimerization of the CXCR4 receptor and the recruitment of ??arrestin2 to agonist?activated G?protein?coupled receptors. This noninvasive and homogeneous assay provides a robust and sensitive proteomic platform with applications for basic
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