- ￥13900 - 23500
- TargetMol
- 美国
- T11554
- 2025年07月16日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
Cathepsin Inhibitor 2
- 库存：
10
- 供应商：
TargetMol
- CAS号：
1017931-53-1
- 规格：
50 mg/25 mg/100 mg
| 规格： | 50 mg | 产品价格： | ￥18300.0 |
|---|---|---|---|
| 规格： | 25 mg | 产品价格： | ￥13900.0 |
| 规格： | 100 mg | 产品价格： | ￥23500.0 |
Product Introduction
Bioactivity
英文名:Cathepsin Inhibitor 2
描述:Cathepsin Inhibitor 2 is a potent Cathepsin S inhibitor (Ki: <20 nM).
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文献和实验, which activates both pro-uPA and latent MMPs, and cleaves the MMP inhibitor TIMP-2. Moreover, cathepsin B, which is expressed by ovarian cancer cells, appears to facilitate the action of uPA, most likely by activating pro-uPA (8 ).
定； LEUPEPTINE Inhibition spectrum: inhibits serine (trypsin (Ki=13 µM), plasmin, porcine kallikrein) and cysteine proteinases (papain, cathepsin B). Does not inhibit chymotrypsin and thrombin. Mechanism of action: Competitive and reversible inhibitor
Computational Analysis of Activity and Selectivity Cliffs
is described and a cathepsin inhibitor set is used to discuss key aspects of the analysis. Combining a numerical scoring scheme and graphical visualization of molecular networks, the approach enables the identification of different local SAR and SSR
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