公告提醒:爱必信所有产品和服务仅用于科学研究,不用于临床应用及其他用途提供产品和服务(也不为任何个人提供产品和服务)! 抗体描述: 产品名称:Rabbit anti-MAGED1 Polyclonal Antibody 产品别名:MAGED1抗体 宿主:Rabbit 反应种属:Human;Mouse;Rat 克隆性:Polyclonal Antibody 保存方法:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles 产品描述:MAGE-D1, also known as NRAGE or Dlxin-1, is a member of the MAGE family of proteins. Identified as a p75 neurotrophin receptor intracellular binding protein, MAGE-D1 induces developmental apoptosis of motoneurons, and is required for p75NTR-dependent apoptosis in sympathetic neurons. It is suggested that MAGE-D1 can suppress the motility and adhesion response of tumor cells. By forming a hetercomplex with Dlx/Msx family homeodomain proteins and Necdin, MAGE-D1 modulates the function of Dlx/Msxhomeodomain during terminal differentiation and maturation of neurons. MAGE-D1 is also involved in the phosphorylation of IKK-alpha/beta, and subsequent transcriptional activation of the p65 subunit of NF-kappaB, via the XIAP-Tak1-Tab1 complex. (20100315, 19639218, 17453828, 15272023) G. 用途范围: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000 产品信息订购:
产品货号 |
产品名称 |
规格 |
价格 |
大包装及货期 |
abs135755 |
Rabbit anti-MAGED1 Polyclonal Antibody |
100ug |
2300.00 |
立即咨询 |
abs135755 |
Rabbit anti-MAGED1 Polyclonal Antibody |
50ug |
1500.00 |
立即咨询 |
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