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- 技术资料
- 抗体名：
Collagen III抗体
- 抗体英文名：
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- 靶点：
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- 浓度：
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- 应用范围：
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- 宿主：
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- 适应物种：
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- 保质期：
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- 抗原来源：
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- 目录编号：
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- 级别：
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- 库存：
现货
- 供应商：
爱必信(上海)生物科技有限公司
- 标记物：
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- 克隆性：
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- 保存条件：
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
- 形态：
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- 免疫原：
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- 规格：
100ug/50ug
| 规格： | 100ug | 产品价格： | ￥2300.0 |
|---|---|---|---|
| 规格： | 50ug | 产品价格： | ￥1500.0 |
| 描述 | Defects in COL3A1 are a cause of Ehlers-Danlos syndrome type 3 (EDS3) [MIM:130020]; also known as benign hypermobility syndrome. EDS is a connective tissue disorder characterized by hyperextensible skin, atrophic cutaneous scars due to tissue fragility and joint hyperlaxity. EDS3 is a form of Ehlers-Danlos syndrome characterized by marked joint hyperextensibility without skeletal deformity. |
| 别名 | Collagen III抗体;Alpha 1 type III collagen, Alpha1 (III) collagen, CO3A1_HUMAN, COL 3A1, COL3A1, Collagen alpha 1(III) chain, Collagen alpha-1(III) chain, Collagen III alpha 1 chain precursor, Collagen III alpha 1 polypeptide, Collagen type III alpha 1 (Ehlers Danlos syndrome type IV autosomal dominant), Collagen type III alpha 1, Collagen type III alpha 1 chain, Collagen type III alpha, Collagen, fetal, EDS4A, Ehlers Danlos syndrome type IV, autosomal dominant, Fetal collagen, Type III collagen, |
| 宿主 | Rabbit |
| 特异性 | Collagen III Antibody detects endogenous levels of total Collagen III. |
| 反应种属 | Human;Mouse;Rat |
| 预测反应种属 | Chicken;Rabbit;Sheep;Dog;Horse |
| 应用 | WB 1:1000, IHC 1:50-1:200, IF 1:100-1:500, ELISA(peptide) 1:20000-1:40000 |
| 分子量 | Predicted molecular weight: 139kD Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
| 免疫原 | A synthesized peptide derived from Human COL3A1(Accession P02461), corresponding to amino acid residues R97-R119. |
| 浓度 | 1mg/ml |
| 纯化方法 | The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin . |
| 类型 | Polyclonal Antibody |
| 储存/保存方法 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles |
| 存储溶液 | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt. |
| 背景说明 | Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the RhoA pathway by coupling ADGRG1 to GNA13 and possibly GNA12. |
| 翻译后修饰 | Proline residues at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.O-linked glycan consists of a Glc-Gal disaccharide bound to the oxygen atom of a post-translationally added hydroxyl group. |
| 细胞定位 | Endoplasmic reticulum;Extracellular region or secreted; |
| UniProt | P02461 |
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文献和实验- Interleukin-1α leads to growth hormone deficiency in adamantinomatous craniopharyngioma by targeting pericytes: implication in pituitary fibrosisJian Mao, Binghui Qiua, Fen Mei, Fan Liu, Zhanpeng Feng, Jun Fan, Jing Nie, Lijun Huang, Xixian Liao, Zhenhao Wang, Jiahui Zeng, Zelin Weng, Nailiang Zang, Songtao Qia, Yun Bao
Metabolism. 2019 Dec 01 .
大鼠III型胶原(Collagen III)ELISA试剂盒 说明书
上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 大鼠 III 型胶原 (Collagen III)ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和其它生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗大鼠 Collagen III 单抗包被于酶标板上，标准品和样品中的 Collagen III 与单抗结合，加入
小鼠III型胶原蛋白(Collagen III)ELISA试剂盒 说明书
上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 小鼠III 型胶原蛋白 ( Collagen III )ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和其它生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗小鼠 Collagen III 单抗包被于酶标板上，标准品和样品中的
Assays of Proteoglycan and Collagen Degradation in Cultures of Rabbit Cartilage Explants
Cultures of cartilage explants have long been used to study the effects of modulators of extracellular matrix degradation. We present a simple and rapid assay system, based on culture of rabbit cartilage explants, which permits study
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