描述:SC 57461A is a potent and selective inhibitor of LTA4 hydrolase. This compound does not inhibit other enzymes of the arachidonic acid cascade including COX-1, COX-2, LTC4 synthase and 5-lipoxygenase. SC 57461A potently inhibits LTB4 production in whole blood (IC50 = 49 nM).
应用:A potent and selective inhibitor of LTA4 hydrolase