Auxinole,86445-22-9

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抑制剂描述：

产品名称：Auxinole

产品别名：见爱必信官网

英文别名：Auxinole

靶点：Others

CAS：86445-22-9

纯度：98%

外观：见爱必信官网

保存方法：Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.

描述：Auxinole is a potent auxin antagonist of TIR1/AFB receptors, binding TIR1 to block the formation of the TIR1-IAA-Aux/IAA complex and so inhibits auxin-responsive gene expression.

溶解性：DMSO : ≥ 125 mg/mL (388.96 mM)
Ethanol : 12.5 mg/mL (38.90 mM; Need ultrasonic)

体外研究：

Auxinole is a potent auxin antagonist of TIR1/AFB receptors, and binds TIR1 to block the formation of the TIR1-IAA-Aux/IAA complex and then inhibits auxin-responsive gene expression. In addition, Auxinole competitively inhibits various auxin responses in planta. Auxinole causes reduction in IAA-triggered depolarization in root hair cells. Auxinole (20 µM) also represses the transient increase in [Ca2+]cyt completely, and blocks Ca2+ response.

体内研究：

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