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Diethyl-pythiDC,1821370-70-0

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  • ¥2911 - 10319
  • 爱必信(absin)
  • 上海
  • abs821263
  • 2025年07月15日
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  • 企业认证

    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.

    • 库存

      99

    • 供应商

      爱必信(上海)生物科技有限公司

    • CAS号

      1821370-70-0

    • 规格

      25mg/5mg

    规格:25mg产品价格:¥10319.0
    规格:5mg产品价格:¥2911.0

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    抑制剂描述:

    产品名称:Diethyl-pythiDC

    产品别名:见爱必信官网

    英文别名:Diethyl-pythiDC

    靶点:Others

    CAS:1821370-70-0

    纯度:98%

    外观:见爱必信官网

    保存方法:Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.

    描述:Diethyl-pythiDC is an inhibitor of collagen prolyl 4-hydroxylases (CP4Hs).

    溶解性:

    体外研究:

    Diethyl-pythiDC inhibits CP4H activity in cultured cells at concentrations that do not cause iron deficiency. MDA-MB-231 cells are treated with biheteroaryl dicarboxylates, and assayed for cytotoxicity and indicators of iron deficiency. None of the esterified biheteroaryl dicarboxylates exhibited cytotoxic activity at high micromolar concentrations. Cells treated with dihydroxybenzoate (EDHB demonstrate a strong iron-deficient phenotype. In contrast, cells treated with Diethyl-pythiDC (Diethyl pythiDC) appear to be normal at concentrations as high as 500 µM. Treatment with Diethyl-pythiDC and low levels of diethyl pyimDC does not affect the level of TfR, HIF-1α, or ferritin.

    体内研究:Diethyl-pythiDC inhibits CP4H activity in cultured cells at concentrations that do not cause iron deficiency. MDA-MB-231 cells are treated with biheteroaryl dicarboxylates, and assayed for cytotoxicity and indicators of iron deficiency. None of the esterified biheteroaryl dicarboxylates exhibited cytotoxic activity at high micromolar concentrations. Cells treated with dihydroxybenzoate (EDHB demonstrate a strong iron-deficient phenotype. In contrast, cells treated with Diethyl-pythiDC (Diethyl pythiDC) appear to be normal at concentrations as high as 500 µM. Treatment with Diethyl-pythiDC and low levels of diethyl pyimDC does not affect the level of TfR, HIF-1α, or ferritin.

    产品信息订购:

      产品货号   产品名称   规格 价格 大包装及货期
      abs821263   Diethyl-pythiDC   5mg   2911.00   立即咨询
      abs821263   Diethyl-pythiDC   25mg   10319.00   立即咨询

    产品更多信息请进入爱必信(absin)商城查看》》》



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    图标文献和实验
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    • LIPID EXTRACTION GENERAL METHODOLOGIES

      in various solvents, it is necessary to jump to 1879 when Franz von Soxhlet described the first method based on an automatic solvent extraction (diethyl ether) for milk lipids (Die gewichtsanalytische Bestimmung des Milchfettes, Dingler's Polytechnisches J

    • StreamlinedDNAExtractionProtocol

      and extraction buffers. 1.Add Diethyl Dithiocarbamic Acid Sodium salt (4 mg/ml) and RNAase A (100 μg/ml) to an aliquot of Grinding Buffer, and B-mercaptoethanol (1%) to an aliquot of Lysis Buffer (see below). 2.Use a single newly emerged, still rolled

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    ¥2911 - 10319