- ￥398 - 849
- 爱必信(absin)
- 上海
- abs818914
- 2025年07月09日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
- 英文名：
Sodium heparin；Sodium heparinate
- 库存：
99
- 供应商：
爱必信(上海)生物科技有限公司
- CAS号：
9041-08-1
- 规格：
500mg/100mg
| 规格： | 500mg | 产品价格： | ￥849.0 |
|---|---|---|---|
| 规格： | 100mg | 产品价格： | ￥398.0 |
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抑制剂描述： 产品名称：Heparin sodium salt 产品别名：见爱必信官网 英文别名：Heparin sodium salt 靶点：Thrombin CAS：9041-08-1 纯度：98% 外观：见爱必信官网 保存方法：Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. 描述：Heparin sodium salt (Sodium heparin) is an anticoagulant which binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin factor IIa and factor Xa. Heparin sodium salt significantly inhibits exosome-cell interactions. 溶解性：Water ：100mg/ml 体外研究： Heparin is widely used as an anticoagulant drug based on its ability to accelerate the rate at which antithrombin inhibits serine proteases in the blood coagulation cascade. Heparin and the structurally related heparan sulfate are complex linear polymers comprised of a mixture of chains of different length, having variable sequences. Heparin interactes most tightly with peptides containing a complementary binding site of high positive charge density. Heparin and heparan sulfate predominantly exhibit linear helical secondary structures with sulfo and carboxyl groups displayed at defined intervals and in defined orientations along the polysaccharide backbone. Heparin resembles DNA as both are highly charged linear polymers that behave as polyelectrolytes. Heparin is believed to function as an anticoagulant primarily through its interaction with AT III by enhancing AT-III-mediated inhibition of blood coagulation factors, including thrombin and factor Xa. Heparin binds to AT III and thrombin in a ternary complex, increasing the bimolecular rate constant for the inhibition of thrombin by a factor of 2000. Heparin is principally located in the granules of tissue mast cells that are closely associated with the immune response. Heparin makes numerous contacts with both FGF-2 and FGFR-1 stabilizing FGF–FGFR binding. Heparin also makes contacts with the FGFR-1 of the adjacent FGF–FGFR complex, thus seeming to promote FGFR dimerization. 体内研究：
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文献和实验for the marketing of this agent vs low molecular weight heparin (LMWH) or yet to come oral direct anti-Xa or direct anti-IIa with regard to pharmacoeconomics.
常用化学试剂分子量 Molecular Weights of Commonly Used Chemicals
.1 Sodium iodide 149.89 dCTP, sodium salt 467.2 Sodium Dodecyl Sulfate 288.38 Dithiothreitol 154.24 Sodium Phosphate, monohydrate 137.99
syringe containing 0.5 ml of sodium heparin (1000 units/ml). The blood may be collected in a heparinized Vacutainer, 10 and transferred to a syringe. Bend a clean, covered 18 gauge needle to a 45° angle and place on the syringe. Invert the syringe (needle
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