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- 详细信息
- 技术资料
- 保存条件:
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
- 库存:
99
- 供应商:
爱必信(上海)生物科技有限公司
- CAS号:
2070014-98-9
- 规格:
10mg/5mg
| 规格: | 10mg | 产品价格: | ¥2963.0 |
|---|---|---|---|
| 规格: | 5mg | 产品价格: | ¥1940.0 |
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抑制剂描述: 产品名称:IFN alpha-IFNAR-IN-1 hydrochloride 产品别名:见爱必信官网 英文别名:IFN alpha-IFNAR-IN-1 hydrochloride 靶点:IFNAR CAS:2070014-98-9 纯度:>98% 外观:见爱必信官网 保存方法:Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution. 描述: IFN alpha-IFNAR-IN-1 hydrochloride is a nonpeptidic, low-molecular-weight inhibitor of the interaction between IFN-α and IFNAR; inhibit MVA-induced IFN-α responses by BM-pDCs (IC50=2-8 uM). IC50 value: Target: IFN alpha-IFNAR interaction inhibitor IFN alpha-IFNAR-IN-1 specifically inhibits MVA-induced IFN-α responses by BM-pDCs. IFN alpha-IFNAR-IN-1 inhibited the IFN-α responses that were elicited after treatment with CpG2216, stimulation with poly(I:C), and infection with VSV-M2, whereas the total IL-12 production was notably less affected under those conditions. IFN alpha-IFNAR-IN-1 exerts immunosuppressive activity by the direct interaction with IFN-α . 溶解性:DMSO : 125 mg/mL (395.74 mM; Need ultrasonic) 体外研究: 体内研究:
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