- ￥481 - 1209
- 爱必信(absin)
- 上海
- abs816974
- 2025年07月07日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
- 保质期：
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
- 英文名：
Corticosterone；17-Deoxycortisol； 11β,21-Dihydroxyprogesterone；Kendall's compound B
- 库存：
7
- 供应商：
爱必信(上海)生物科技有限公司
- CAS号：
50-22-6
- 规格：
25mg/5mg
| 规格： | 25mg | 产品价格： | ￥1209.0 |
|---|---|---|---|
| 规格： | 5mg | 产品价格： | ￥481.0 |
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抑制剂描述： 产品名称：Corticosterone 产品别名：见爱必信官网 英文别名：Corticosterone 靶点：MAT CAS：50-22-6 纯度：＞98% 外观：见爱必信官网 保存方法：Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. 描述： Corticosterone is a sensitive inhibitor of monoamine transport. 溶解性：DMSO : 34.7 mg/mL (100 mM) 体外研究： Corticosterone, via SGK phosphorylation of GDI at Ser-213, increases the formation of GDI-Rab4 complex, facilitating the functional cycle of Rab4 and Rab4-mediated recycling of AMPARs to the synaptic membrane. It enhances AMPAR-mediated miniature excitatory postsynaptic current (mEPSC) amplitude and surface expression of GluR1 and GluR2 subunits in hippocampal neurons, increases the surface mobility and synaptic content of AMPAR GluR2 subunits, and enhances L-type calcium currents in CA1 pyramidal neurons. Corticosterone operates through mineralocorticoid receptors and glucocorticoid receptors, both of which belong to the family of nuclear receptors that bind to response elements in the DNA, thus modifying the activity of responsive genes. 体内研究：Corticosterone plays an important role in regulating neuronal functions of the limbic system. After stress, the level of stress hormones such as corticosterone is markedly increased. Corticosterone exerts a time- and region-specific action on cellular physiology of limbic neurons.
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文献和实验- Corticosterone Enhances the AMPK-Mediated Immunosuppressive Phenotype of Testicular Macrophages During Uropathogenic Escherichia coli Induced OrchitisZhengguo Zhang, Ziming Jiang, Yiming Zhang, Yu Zhang, Yan Yan, Sudhanshu Bhushan, Andreas Meinhardt, Zhihai Qin, Ming Wang
Front Immunol. 2021 Jan 08 .
影响因子： 5.085
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