保存方法:Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
描述:N/A
溶解性:Soluble in ethanol and DMSO
体外研究:
Osalmid is shown to be 10-fold more active in inhibiting RR activity than hydroxyurea, and significantly inhibits HBV DNA and cccDNA synthesis in HepG2.2.15 cells. Osalmid significantly inhibits HBV DNA replication in a time- and dose-dependent manner.
体内研究:Osalmid significantly reduces RR activity and HBV DNA replication in vivo.