Bergapten

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抑制剂描述：

产品名称：Bergapten

产品别名：见爱必信官网

英文别名：Bergapten

靶点：Coumarins

CAS：484-20-8

纯度：99%

外观：见爱必信官网

保存方法：Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.

描述：

Bergapten is a psoralen that can be photoactivated and is capable of crossing-linking DNA, covalently modifying proteins and lipids, and consequently inhibiting cell replication.

溶解性：DMSO ：5mg/mL(23.12mM)

体外研究：

Bergapten acts as a natural antitumoral agent, able to deplete ERα from breast cancer tamoxifen-sensitive and resistant cells, thereby retraining the effect of membrane signals targeting ERα and in such way its mitogenic potentiality.

体内研究：Bergapten can effectively protect C57BL/6J mice from acetaminophen (APAP)-induced hepatotoxicity and possesses an antioxidative activity, and does not cause liver injury at the protective doses.

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