溶解性:DMSO 38 mg/mL (68.39 mM) Ethanol 15 mg/mL (26.99 mM) Water slightly soluble or insoluble
体外研究:
OICR-9429 binds WDR5 with high affinity (Kd=93±28 nM) and competitively disrupts its interaction with a high-affinity Wdr5-interacting (WIN) peptide of MLL (Kdisp=64±4 nM).